Nucleotide Sequence of a Cloned Hepatitis B Virus Genome, Subtype ayr: Comparison with Genomes of the Other Three Subtypes
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چکیده
By H I R O A K I O K A M O T O , 1 M I T S U N O B U I M A I , 1 M A Y U M I S H I M O Z A K I , 1 Y U J I H O S H I , 2 H I S A O I I Z U K A , z T O H R U G O T A N D A , 3 F U M I O T S U D A , 3 Y U Z O M I Y A K A W A * AND M A K O T O M A Y U M I 1. llmmunology Division, Jichi Medical School, Minamikawachi-MachL Tochigi-Ken 329-04, 2Japanese Red Cross Blood Center, Saitama-Ken 362, 3Hepatitis Division, The Tokyo Metropolitan Institute of Medical Science, Tokyo 113 and 4Institute of Immunology, Tokyo 112, Japan
منابع مشابه
Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes.
The complete nucleotide sequences of the DNA of three hepatitis B virus (HBV) genomes of subtype adw, cloned from plasma samples of asymptomatic carriers living in the mainland and Okinawa Prefecture of Japan and Indonesia were determined. All three comprised 3215 bp and differed in sequence by only 3.9 to 5.6%. When these isolates were compared with the reported sequences of two HBV genomes of...
متن کاملNucleotide sequence of a cloned hepatitis B virus genome, subtype ayr: comparison with genomes of the other three subtypes.
The entire nucleotide sequence of genomic DNA was determined for hepatitis B virus (HBV) of subtype ayr, which had been derived from the blood of a Japanese asymptomatic carrier. The genome was 3215 nucleotides long, and differed in DNA sequence by 10% from that of subtypes adw or ayw, but by only 2% from that of subtype adr. Amino acid sequences coded for by the S, C, P and X genes, as well as...
متن کاملNucleotide Sequence of a Cloned Hepatitis B Virus Genome, Subtype ayr: Comparison with Genomes of the Other Three Subtypes
By H I R O A K I O K A M O T O , 1 M I T S U N O B U I M A I , 1 M A Y U M I S H I M O Z A K I , 1 Y U J I H O S H I , 2 H I S A O I I Z U K A , z T O H R U G O T A N D A , 3 F U M I O T S U D A , 3 Y U Z O M I Y A K A W A * AND M A K O T O M A Y U M I 1. llmmunology Division, Jichi Medical School, Minamikawachi-MachL Tochigi-Ken 329-04, 2Japanese Red Cross Blood Center, Saitama-Ken 362, 3Hepat...
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We have sequenced the complete genome of a hepatitis B virus (A938) obtained from serum of a patient with a high-titred, HBeAg-positive infection. The DNA sequence (3221 bp) was 99.2%, 95.4%, 90.9% and 89% homologous to the sequences of subtypes adw2 (3), adw (1), adr (5) and ayw (9). The adw2 subtype of the A938 virus was verified by analysing the subtype specific amino acids of the major surf...
متن کاملThe complete nucleotide sequences of the cloned hepatitis B virus DNA; subtype adr and adw.
The complete nucleotide sequences of two different subtypes (adr and adw) of hepatitis B virus (HBV) DNA cloned in E. coli were determined. The sequence of the viral genome of the adr clone was 3188 nucleotides long, and that of the adw clone was 3200 nucleotides long. The adr and adw clones differed from the reported cloned ayw HBV DNA (3182 nucleotides long) in 11.2% and 10.0% of nucleotides,...
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